Opportunity Information: Apply for HRSA 23 077
The National Center for Newborn Screening System Excellence (NBS Excel) funding opportunity (HRSA 23-077) is a discretionary Health Resources and Services Administration (HRSA) cooperative agreement run by the U.S. Department of Health and Human Services. Its core aim is to fund a single national organization that can act as a central hub to strengthen and improve newborn screening (NBS) systems across the entire country. Rather than funding many separate state projects, this opportunity is designed to support state NBS programs and their partners at a systems level, helping them solve common problems, spread effective practices, and improve consistency and quality nationwide.
The work is organized around four major responsibilities. First, the funded organization is expected to provide national leadership along with technical assistance and quality improvement expertise. In practical terms, that means serving as a go-to resource for states and stakeholders that need help with program operations, performance management, continuous quality improvement methods, and the implementation of proven approaches that raise screening effectiveness and reliability. Because it is a cooperative agreement, HRSA typically plays an active role in shaping priorities, monitoring progress, and collaborating with the awardee, which signals an expectation of ongoing coordination rather than a hands-off grant.
Second, NBS Excel is meant to strengthen health equity in newborn screening by collecting and using data to identify barriers that prevent equitable access to services for all infants and families. This emphasis on data suggests the awardee should be able to gather information across jurisdictions, analyze gaps and disparities, and translate findings into actionable recommendations. The intent is to move beyond anecdotal concerns and pinpoint where inequities arise in the screening system (for example, differences in access, timeliness, follow-up, communication, or support services), then help stakeholders use that information to drive improvements.
Third, the opportunity explicitly focuses on enhancing state performance in newborn screening. This performance focus implies the national center will help states improve measurable aspects of NBS, such as the quality and timeliness of screening processes, the effectiveness of follow-up and confirmatory testing pathways, and the overall coordination among laboratories, clinicians, public health programs, and other partners. While the source text does not list specific metrics, the language signals an expectation that the awardee will support states in strengthening real-world outcomes and operational benchmarks, likely through tailored technical assistance, performance improvement strategies, and sharing best practices.
Fourth, and notably, the grant places strong emphasis on meaningful engagement and leadership by families and individuals affected by heritable disorders throughout the newborn screening system. The funded organization is expected to provide subject matter expertise, technical assistance, training, education, and additional resources specifically for youth and families. The purpose is to promote active participation and leadership by families at all levels of NBS, which commonly includes involvement in advisory bodies, policy discussions, system design, quality improvement initiatives, and communication strategies. This component highlights that newborn screening is not only a laboratory and public health function, but also a family-centered system that must communicate clearly, support informed engagement, and incorporate lived experience into improvement efforts.
Eligibility is broad and includes state governments, federally recognized tribal governments, other tribal organizations, and nonprofit organizations with 501(c)(3) status (excluding institutions of higher education), along with other entities as clarified in the full announcement. Only one award is expected, reinforcing the national-center model. The funding instrument is a cooperative agreement (rather than a standard grant), which generally indicates HRSA anticipates substantial involvement, coordination, and shared responsibility for achieving the program goals. The opportunity was created on November 14, 2022, with an original application closing date of February 13, 2023. The listing indicates an award ceiling of 0, which typically means the ceiling was not specified in the provided excerpt or was described elsewhere in the full notice rather than indicating no funding.
Overall, HRSA-23-077 NBS Excel is structured to build nationwide capacity for newborn screening excellence by combining leadership and technical support for states, a data-driven focus on equity barriers, targeted efforts to raise measurable program performance, and a strong commitment to equipping families and individuals with heritable disorders to be informed partners and leaders in the newborn screening system.Apply for HRSA 23 077
- The Department of Health and Human Services, Health Resources and Services Administration in the health sector is offering a public funding opportunity titled "National Center for Newborn Screening System Excellence (NBS Excel)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.110.
- This funding opportunity was created on Nov 14, 2022.
- Applicants must submit their applications by Feb 13, 2023. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The number of recipients for this funding is limited to 1 candidate(s).
- Eligible applicants include: State governments, Native American tribal governments (Federally recognized), Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Others (see text field entitled Additional Information on Eligibility for clarification).
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